Als facial symptoms
Amyotrophic lateral sclerosis ALS damages the nerves in the brain and spinal cord. These nerves control the ability to move muscles. ALS slowly gets worse. Over time, it often becomes harder to walk, speak, eat, swallow, and breathe. But some people live for many years, even decades, after they learn that they have ALS. Finding out that you have ALS may be overwhelming.
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Motor Neuron Diseases (ALS, SMA, PBP, PLS)
Amyotrophic Lateral Sclerosis (ALS) | PeaceHealth
ALS affects the u pper motor neurons , which are in the brain, and the lower motor neurons , which are in the spinal cord and brainstem. Upper motor neuron degeneration generally causes spasticity tightness in a muscle , slowness of movement, poor balance and incoordination, while lower motor neuron degeneration causes muscle weakness, muscle atrophy shrinkage of muscles and twitching fasciculations. These can occur in combination in ALS, as upper and lower motor neurons are affected at the same time. ALS can affect people of any age, though it usually strikes in late middle age. ALS typically announces itself with persistent weakness or spasticity in an arm or leg 80 percent of all cases , causing difficulty using the affected limb. Sometimes in about 20 percent of all cases the problem presents first in the muscles controlling speech, producing alterations in the vocal quality, or swallowing, which may lead to coughing and choking. The disease can also affect the muscles of the face, leading to problems such as incomplete eye closure and drooling.
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Stages of ALS
Try out PMC Labs and tell us what you think. Learn More. Amyotrophic lateral sclerosis ALS is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord.
Motor Neuron Diseases MNDs are a group of progressive neurological disorders that destroy motor neurons, the cells that control essential voluntary muscle activities such as speaking, walking, breathing and swallowing. Normally, messages from nerve cells in the brain, called upper motor neurons, are transmitted to nerve cells in the brainstem and spinal cord called lower motor neurons and from there to particular muscles. Upper motor neurons direct lower motor neurons to produce movements such as walking or chewing. Lower motor neurons control movement in the arms, legs, chest, face, throat and tongue.
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